Radiographic Follow-up of Transforaminal Lumbar Fusion with Silicon Nitride Spacers: A Case Report of Two Patients

Radiographic Follow-up of Transforaminal Lumbar Fusion with Silicon Nitride Spacers: A Case Report of Two Patients

Author(s): Youssef JA, Myhre SL, Bal BS J Musculoskelet Disord Treat 2:009

The objective of this study was to evaluate the performance of the Amedica – TL fusion device in two patients with a history of posterior lumbar interbody spinal fusion… Read More »

Ceramics and ceramic coatings in orthopaedics

Author(s): B.J. McEntire, B.S. Bal, M.N. Rahaman, J. Chevalier, G. Pezzotti Journal of the European Ceramic Society, Volume 35, Issue 16, December 2015

Advanced bioceramics have played integral roles in treatment modalities for damaged or diseased human joints and osseous defects. This paper reviews the use… Read More »

Bioceramics for Hip Joints: The Physical Chemistry Viewpoint

Author(s): Pezzotti G. Materials (Basel). 2014;7:4367–4410.

Which intrinsic biomaterial parameter governs and, if quantitatively monitored, could reveal to us the actual lifetime potential of advanced hip j… Read More »

Bioceramics for Hip Joints: The Physical Chemistry Viewpoint

Author(s): Pezzotti G. Materials 2014, 7(6), 4367-4410; doi:10.3390/ma7064367

Which intrinsic biomaterial parameter governs and, if quantitatively monitored, could reveal to us the actual lifetime potential of advanced hip j… Read More »

Bearing surfaces in hip replacement – Evolution and likely future

Author(s): Kumar N, Arora GNC, Datta B. Med J Armed Forces India. 2014 Oct;70(4):371-6. doi: 10.1016/j.mjafi.2014.04.015. Epub 2014 Aug 4.

Total hip arthroplasty has evolved from the first total hip arthroplasty in 1938, through the revolutionization of hip arthroplasty by principles… Read More »

Future bearing surfaces in total hip arthroplasty

Author(s): Chang JD. Clin Orthop Surg. 2014;6(1):110–6. doi: 10.4055/cios.2014.6.1.110. Epub 2014 Feb 14.

One of the most important issues in the modern total hip arthroplasty (THA) is the bearing surface. Extensive research on bearing surfaces is bein… Read More »

Synthesis, Characterizations and in Vitro Assessment of the Cytotoxicity and Genotoxicity of Novel Silicon Nitride-Based Porous Ceramics

Author(s): Hnatko M, Lenčéš Z, Čopan P, Birošová L, Matejov P, Jantová S. Mater Sci Appl. 2013;4(7):407–418.

Porous Si3N4-SiO2-based ceramics with different porosity were prepared via free sintering of Si3N4 on air with an addition of semolina (5, 10 and … Read More »

An Overview of Silicon Nitride as a Novel Biomaterial

Author(s): Bryan J. McEntire, Alan Lakshminarayanan, PhD, B. Sonny Bal, M.D., MBA, JD and Thomas J. Webster, PhD. Poster presented at the Innovations in Biomedical Materials 2012 Meeting, Raleigh, NC.

For over thirty years, silicon nitride (Si3N4) has been used extensively in a wide array of demanding industrial applications such as precision be… Read More »

Orthopedic Applications of Silicon Nitride Ceramics

Author(s): B.S. Bal, M.N. Rahaman Acta Biomater. 2012 Aug;8(8):2889-98. doi:10.1016/j.actbio.2012.04.031. Epub 2012 Apr 26.

Silicon nitride (Si3N4) is a ceramic material developed for industrial applications that demand high strength and fracture resistance under extreme operating conditions… Read More »

Fabrication and Evaluation of SixNy Coatings for Total Joint Replacements

Author(s): Olofsson J, Pettersson M, Teuscher N, Heilmann A, Larsson K, Grandfield K, Persson C, Jacobson S, Engqvist H. J Mater Sci Mater Med. 2012 Aug;23(8):1879-89. doi: 10.1007/s10856-012-4625-3. Epub 2012 Jun 12.

Wear particles from the bearing surfaces of joint implants are one of the main limiting factors for total implant longevity. Si3N4 is a potent… Read More »

Evaluation of silicon nitride as a wear resistant and resorbable alternative for total hip joint replacement

Author(s): Olofsson J, Grehk TM, Berlind T, Persson C, Jacobson S, Engqvist H. Biomatter. 2012 Apr-Jun;2(2):94-102. doi: 10.4161/biom.20710.

Many of the failures of total joint replacements are related to tribology, i.e., wear of the cup, head and liner. Accumulation of wear particles a… Read More »

Silicon nitride films for the protective functional coating: Blood compatibility and biomechanical property study

Author(s): Shi Z, Wang Y, Du C, Huang N, Wang L, Ning C. J Mech Behav Biomed Mater. 2012 Dec;16:9-20. doi: 10.1016/j.jmbbm.2012.06.020. Epub 2012 Aug 21.

Behaviors of silicon nitride films and their relation to blood compatibility and biomechanical have been interesting subjects to researchers. A sy… Read More »

Evaluation of silicon nitride as a wear resistant and resorbable alternative for total hip joint replacement

Author(s): Olofsson J, Grehk TM, Berlind T, Persson C, Jacobson S, Engqvist H. Biomatter. 2012 Apr-Jun;2(2):94-102. doi: 10.4161/biom.20710.

Many of the failures of total joint replacements are related to tribology, i.e., wear of the cup, head and liner. Accumulation of wear particles a… Read More »

Protein-repellent silicon nitride surfaces: UV-induced formation of oligoethylene oxide monolayers

Author(s): Rosso M, Nguyen AT, de Jong E, Baggerman J, Paulusse JM, Giesbers M, Fokkink RG, Norde W, Schroën K, van Rijn CJ, Zuilhof H. ACS Appl Mater Interfaces. 2011;3(3):697–704.

The grafting of polymers and oligomers of ethylene oxide onto surfaces is widely used to prevent nonspecific adsorption of biological material on … Read More »

Cytocompatibility of high strength non-oxide ceramics

Author(s): Cappi B, Neuss S, Salber J, Telle R, Knüchel R, Fischer H. J Biomed Mater Res A. 2010 Apr;93(1):67-76. doi: 10.1002/jbm.a.32527.

Oxide ceramic materials like alumina (Al(2)O(3)) and zirconia (ZrO(2)) are frequently used for medical applications like implants and prostheses b… Read More »

Silicon Nitride Ceramics: The Future of Orthopaedic Surgery

Author(s): McEntire BJ. Ceramic Industry;Sep2010, Vol. 160 Issue 9, p26

The article offers information on silicon nitride ceramics, the next platform technology in orthopaedic devices industry. It notes how ceramic mat… Read More »

Ceramics for Medical Applications: A Picture for the Next 20 Years

Author(s): Chevalier J, Gremillard L. Ceram Soc. 2009;29(7):1245–1255. doi:10.1016/j.jeurceramsoc.2008.08.025

High-tech ceramics have always been associated to medical devices: they are used today as femoral heads and acetabular cups for total hip replacem… Read More »

On the possibility of silicon nitride as a ceramic for structural orthopaedic implants – Part I: processing, microstructure, mechanical properties, cytotoxicity

Author(s): Mazzocchi M, Bellosi A. J Mater Sci Mater Med. 2008 Aug;19(8):2881-7. doi: 10.1007/s10856-008-3417-2. Epub 2008 Mar 18.

Notwithstanding the good combination of mechanical and tribological properties, the suitability of silicon nitride for application as prosthesis i… Read More »

Hydroxyapatite Coating on Silicon Nitride Surfaces Using the Biomimetic Method

Author(s): Cecilia Chaves Guedes e Silva, Eliana Cristina da Silva Rigo, Juliana Marchi, Ana Helena de Almeida Bressiani, José Carlos Bressiani. Materials Research, Vol. 11, No. 1, 47-50, 2008.

Silicon nitride based ceramics are promising candidates for biomedical applications due to their chemical and dimensional stability associated to … Read More »

Tissue response around silicon nitride implants in rabbits

Author(s): Guedes e Silva CC, König B Jr, Carbonari MJ, Yoshimoto M, Allegrini S Jr, Bressiani JC. J Biomed Mater Res A. 2008 Feb;84(2):337-43.

The chemical and dimensional stability associated with suitable fracture toughness and propitious tribological characteristics make silicon nitrid… Read More »

Covalent biofunctionalization of silicon nitride surfaces

Author(s): Arafat A, Giesbers M, Rosso M, Sudhölter EJ, Schroën K, White RG, Yang L, Linford MR, Zuilhof H. Langmuir. 2007;23(11):6233–44.

Covalently attached organic monolayers on etched silicon nitride (SixN4; x >/= 3) surfaces were prepared by reaction of SixN4-coated wafers with n… Read More »

Development and cytotoxicity evaluation of SiAlONs ceramics

Author(s): C. Santos , S. Ribeiro, J.K.M.F. Daguano , S.O. Rogero, K. Strecker, C.R.M. Silva. Materials Science and Engineering C 27 (2007) 148–153.

SiAlONs are ceramics with high potential as biomaterials due to their chemical stability, associated with suitable mechanical properties, such as … Read More »

Prototype of a silicon nitride ceramic-based miniplate osteofixation system for the midface

Author(s): Neumann A, Unkel C, Werry C, Herborn CU, Maier HR, Ragoss C, Jahnke K. Otolaryngol Head Neck Surg. 2006 Jun;134(6):923-30.

The favorable properties of silicon nitride (Si3N4) ceramics, such as high mean strength level and fracture toughness, suggest biomedical use as a… Read More »

Prototype of a silicon nitride ceramic-based miniplate osteofixation system for the midface

Author(s): Neumann A, Unkel C, Werry C, Herborn CU, Maier HR, Ragoss C, Jahnke K. Otolaryngol Head Neck Surg. 2006 Jun;134(6):923-30.

The favorable properties of silicon nitride (Si3N4) ceramics, such as high mean strength level and fracture toughness, suggest biomedical use as a… Read More »

In Vivo Biostability of CVD Silicon Oxide and Silicon Nitride Films

Author(s): Maloney JM, Lipka SA, Baldwin SP. Mater Res Soc Proc. 2005;872:J14.3.1.

Low pressure chemical vapor deposition (LPCVD) and plasma enhanced chemical vapor deposition (PECVD) silicon oxide and silicon nitride films were … Read More »

Biocompatibility of Silicon Nitride Ceramic In Vitro. A Comparative Fluorescence-microscopic and Scanning Electron Microscopic Study

Author(s): Neumann A, Jahnke K, Maier HR, Ragoss C. Laryngorhinootologie. 2004 Dec;83(12):845-51.

With regard to its favorable physical properties, silicon nitride ceramic is considered as biomaterial for human medical application. Minor contro… Read More »

Cytotoxic evaluation of silicon nitride-based ceramics

Author(s): C.C. Guedes e Silva, O.Z. Higa, J.C. Bressiani. Materials Science and Engineering C 24 (2004) 643–646. doi:10.1016/j.msec.2004.08.007

Silicon nitride-based ceramics are potential candidates as materials for orthopedic implants due to their chemical stability associated with suita… Read More »

Comparative investigation of the biocompatibility of various silicon nitride ceramic qualities in vitro

Author(s): Neumann A, Reske T, Held M, Jahnke K, Ragoss C, Maier HR. J Mater Sci Mater Med. 2004 Oct;15(10):1135-40.

There is a controversy about the biocompatibility of silicon nitride ceramics contained in the literature, which appears to be related to a factor… Read More »

Histological and microradiographic appearances of Silicon Nitride and Aluminum Oxide in a rabbit femur implantation model

Author(s): A. Neumann, M. Kramps, Chr. Ragoß, H.R. Maier, K. Jahnke. Mat.-wiss. u. Werkstofftech., 35: 569–573. doi: 10.1002/mawe.200400778

Silicon nitride (Si3N4) is a ceramic known for its high performance characterized by fracture toughness, high wear resistance and low coefficie… Read More »

Comparative investigation of the biocompatibility of various silicon nitride ceramic qualities in vitro

Author(s): Neumann A, Reske T, Held M, Jahnke K, Ragoss C, Maier HR. J Mater Sci Mater Med. 2004 Oct;15(10):1135-40.

There is a controversy about the biocompatibility of silicon nitride ceramics contained in the literature, which appears to be related to a factor… Read More »

Cytotoxicity evaluation of ceramic particles of different sizes and shapes

Author(s): Yamamoto A, Honma R, Sumita M, Hanawa T. J Biomed Mater Res A. 2004 Feb 1;68(2):244-56.

When artificial hip or knee joints are implanted in the human body, they release metallic, ceramic, and polymeric debris into the surrounding tiss… Read More »

Enhanced proliferation and osteocalcin production by human osteoblast-like MG63 cells on silicon nitride ceramic discs

Author(s): Kue R, Sohrabi A, Nagle D, Frondoza C, Hungerford D. Biomaterials. 1999 Jul;20(13):1195-201.

The biocompatibility of silicon nitride (Si3N4) was assessed in an in vitro model using the human osteoblast-like MG-63 cell line. Cells were prop… Read More »

Study on the possibility of silicon nitride-silicon nitride as a material for hip prostheses

Author(s): Y.S. Zhou, M. Ohashi, N. Tomita, K. Ikeuchi, K. Takashima. Materials Science and Engineering C5 (1997) 125-129.

In order to study the possibility of silicon nitride-silicon nitride as a material for hip prostheses, the running-in property, the start-… Read More »

Size Matters to Stem Cells

Author(s): Sebastian Bauer, Jung Park, Josef Faltenbacher, Steffen Berger, Klaus von der Mark, and Patrik Schmuki Integr. Biol., 2009, 1, 525, DOI: 10.1039/b908196h

Evaluation of Silicon Nitride as a Substrate for Culture of PC12 Cells: An Interfacial Model for Functional Studies in Neurons

Author(s): Medina Benavente JJ, Mogami H, Sakurai T, Sawada K. PLoS One. 2014;9(2):e90189.

Silicon nitride is a biocompatible material that is currently used as an interfacial surface between cells and large-scale integration devices inc… Read More »

A surface modification strategy on silicon nitride for developing biosensors

Author(s): Diao J, Ren D, Engstrom JR, Lee KH. Anal Biochem. 2005;343(2):322–8.

A surface modification strategy for the use of giant magnetoresistive materials in the detection of protein-protein interactions is developed. Thi… Read More »

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