3D-Additive Deposition of an Antibacterial and Osteogenic Silicon Nitride Coating on Orthopaedic Titanium Substrate

3D-Additive Deposition of an Antibacterial and Osteogenic Silicon Nitride Coating on Orthopaedic Titanium Substrate

Surface topography of silicon nitride affects antimicrobial and osseointegrative properties of tibial implants in a murine model

Human osteoblasts grow transitional Si/N apatite in quickly osteointegrated Si3N4 cervical insert

Radiographic Follow-up of Transforaminal Lumbar Fusion with Silicon Nitride Spacers: A Case Report of Two Patients

Author(s): Youssef JA, Myhre SL, Bal BS J Musculoskelet Disord Treat 2:009

The objective of this study was to evaluate the performance of the Amedica – TL fusion device in two patients with a history of posterior lumbar interbody spinal fusion… Read More »

Ceramics and ceramic coatings in orthopaedics

Author(s): B.J. McEntire, B.S. Bal, M.N. Rahaman, J. Chevalier, G. Pezzotti Journal of the European Ceramic Society, Volume 35, Issue 16, December 2015

Advanced bioceramics have played integral roles in treatment modalities for damaged or diseased human joints and osseous defects. This paper reviews the use… Read More »

Surface modulation of silicon nitride ceramics for orthopaedic applications

Author(s): Bal BS, McEntire BJ, Bock R, Jones E, Rahaman M. Transatlantic Orthopaedic Congress , October 3-5, 2014. New York: ICJR Press; 2014:1–2.

These results show that the surface composition and properties of Si3N4 can be engineered over a wide range Co, from a purely oxide (silica) sur… Read More »

Retrospective Radiographic Review of PEEK and Silicon Nitride Spinal Implants the Same Patient

Author(s): Nabil L. Muhanna , M.D. Northeast Georgia Medical Center IRB Reference Number FY14-08-481

A patient underwent two separate spinal surgeries, the first using two PEEK spinal implants and the second, three years later, using a ceramic silicon nitri… Read More »

In Vivo Bone Formation and Bacterial Infection Between Silicon Nitride Ceramic, PEEK, and Titanium

Author(s): McEntire, B. J., Lakshminarayanan, A., Bal, B. S., Webster, T., Ercan, B., & Gorth, D. Bone Joint J, 95-B(SUPP 15), 129.

Superior bone ingrowth and resistance to bacterial infection are ideal for orthopaedic implants. We compared new bone formation, strength of bone bondi… Read More »

Porous Silicon Nitride Ceramics Designed for Bone Substitute Applications

Author(s): Bodišová K, Kašiarová M, Domanická M, et al. Ceram Int. 2013;39(7):8355–8362.

Porous silicon nitride ceramics having properties similar to the human trabecular bone have been sintered and characterized in order to develop a… Read More »

Orthopedic Applications of Silicon Nitride Ceramics

Author(s): B.S. Bal, M.N. Rahaman Acta Biomater. 2012 Aug;8(8):2889-98. doi:10.1016/j.actbio.2012.04.031. Epub 2012 Apr 26.

Silicon nitride (Si3N4) is a ceramic material developed for industrial applications that demand high strength and fracture resistance under extreme operating conditions… Read More »

Anti-bacterial and Osteointegration Properties of Silicon Nitride, Poly-Ether-Ether-Ketone, and Titanium Implants

Author(s): Webster TJ, Patel AA, Rahaman MN, Sonny Bal B. Acta Biomater. 2012 Dec;8(12):4447-54. doi: 10.1016/j.actbio.2012.07.038. Epub 2012 Jul 31.

Silicon nitride (Si3N4) is an industrial ceramic used in spinal fusion and maxillofacial reconstruction. Maximizing bone formation and minimiz… Read More »

Research Shows Silicon Nitride (Si3N4) Exhibits Antibacterial Properties, Superior Bone Growth and More Effective Bone Attachment Compared to Other Biomaterials, and May Lead to Faster Fusion

Author(s): Skidmore G. Medco Forum. 2012;19(48):1–2.

Introduction: Infection after spine surgery with instrumentation is becoming a common pathology, with reported infection rates ranging from 0.7% to 11.9%, d… Read More »

Silicon Nitride Ceramics: The Future of Orthopaedic Surgery

Author(s): McEntire BJ. Ceramic Industry;Sep2010, Vol. 160 Issue 9, p26

The article offers information on silicon nitride ceramics, the next platform technology in orthopaedic devices industry. It notes how ceramic mat… Read More »

Bone Ingrowth into Porous Silicon Nitride

Author(s): Anderson MC, Olsen R. J Biomed Mater Res A. 2010 Mar 15;92(4):1598-605. doi: 10.1002/jbm.a.32498.

Achieving solid skeletal attachment is a requirement for the clinical success of orthopedic implants. Porous or roughened surfaces and coatings ha… Read More »

Bone growth around silicon nitride implants – An evaluation by scanning electron microscopy

Author(s): C.C. Guedes e Silva, B. König Jr., M.J. Carbonari, M. Yoshimoto, S. Allegrini Jr., J.C. Bressiani. Materials Characterization 5 9(2008) 1339 – 1341.

Silicon nitride has demonstrated to be a potential candidate for clinical applications because it is a non-cytotoxic material and has satisfactory… Read More »

Silicates and Bone Fusion

Author(s): Walid Waked, MD and Jonathan Grauer, MD

Department of Orthopaedics and Rehabilitation Yale University School of Medicine, New Haven, CT Read More »

Silicon and Bone Health

Author(s): R. Jugdaohsingh J Nutr Health Aging. 2007 ; 11(2): 99–110.

Prototype of a silicon nitride ceramic-based miniplate osteofixation system for the midface

Author(s): Neumann A, Unkel C, Werry C, Herborn CU, Maier HR, Ragoss C, Jahnke K. Otolaryngol Head Neck Surg. 2006 Jun;134(6):923-30.

The favorable properties of silicon nitride (Si3N4) ceramics, such as high mean strength level and fracture toughness, suggest biomedical use as a… Read More »

Biocompatibility of Silicon Nitride Ceramic In Vitro. A Comparative Fluorescence-microscopic and Scanning Electron Microscopic Study

Author(s): Neumann A, Jahnke K, Maier HR, Ragoss C. Laryngorhinootologie. 2004 Dec;83(12):845-51.

With regard to its favorable physical properties, silicon nitride ceramic is considered as biomaterial for human medical application. Minor contro… Read More »

Histological and microradiographic appearances of Silicon Nitride and Aluminum Oxide in a rabbit femur implantation model

Author(s): A. Neumann, M. Kramps, Chr. Ragoß, H.R. Maier, K. Jahnke. Mat.-wiss. u. Werkstofftech., 35: 569–573. doi: 10.1002/mawe.200400778

Silicon nitride (Si3N4) is a ceramic known for its high performance characterized by fracture toughness, high wear resistance and low coefficie… Read More »

Differentiation of the human mesenchymal stem cells derived from bone marrow and enhancement of cell attachment by fibronectin

Author(s): Ogura N, Kawada M, Chang WJ, Zhang Q, Lee SY, Kondoh T, Abiko Y. J Oral Sci. 2004 Dec;46(4):207-13.

The ability of human mesenchymal stem cells (hMSC) to differentiate into osteoblasts was examined through the use of osteogenic induction medium… Read More »

Results of 15-Year Clinical Study of Reaction Bonded Silicon Nitride Intervertebral Spacers

Author(s): Sorrell, CC, Hardcastle, PH, Druitt, RK, Howlett, CR, and McCartney, ER. Proceedings of the 7th World Biomaterials Congress, May 17-21, 2004, Sydney, Australia.

Findings: Thirty patients with long-term spinal degeneration problems underwent anterior interbody fusion of the lower spine using reaction bonded silicon n… Read More »

Si3N4-bioglass composites stimulate the proliferation of MG63 osteoblast-like cells and support the osteogenic differentiation of human bone marrow cells

Author(s): Amaral M, Costa MA, Lopes MA, Silva RF, Santos JD, Fernandes MH. Biomaterials. 2002 Dec;23(24):4897-906.

The in vitro osteocompatibility of a novel Si3N4-bioglass composite (70-30% weight proportion) with improved mechanical properties (fracture t… Read More »

The Effect of Silicon Nitride Ceramic on Rabbit Skeletal Cells and Tissue – An In Vitro and In Vivo Investigation

Author(s): Howlett CR, McCartney E, Ching W. Clin Orthop Relat Res. 13030 Jul;(244):293-304.

This article presents a morphologic assessment of the effect of silicon nitride ceramic (Si3N4) on rabbit marrow stromal cells and their different… Read More »

Thirty-day readmissions after elective spine surgery for degenerative conditions among US Medicare beneficiaries

Author(s): Marjoire C WAng, MD, MPH, Mikesh Shivatoki, BSc, Rodney A. Sparapani, PhD, Changbin Guo, PhD, Purushottam W. Laud, PhD, Anne B. Nattinger, MD, MPH

To examine readmissions within 30 days of hospital discharge, reasons for readmission, and predictors of readmission among patients undergoing elective cerv… Read More »

The CASCADE Trial: Effectiveness of Ceramic Versus PEEK Cages for Anterior Cervical Discectomy with Interbody Fusion; Protocol of a Blinded Randomized Controlled Trial

Author(s): Arts MP, Wolfs JFC, Corbin TP. BMC Musculoskelet Disord. 2013;14(1):244.

Background: Anterior cervical discectomy with interbody fusion cages is considered the standard surgical procedure in patients with cervical disc herniation… Read More »

The SNAP trial: a double blind multi-center randomized controlled trial of a silicon nitride versus a PEEK cage in transforaminal lumbar interbody fusion in patients with symptomatic degenerative lumbar disc disorders: study protocol

Author(s): Kersten RF, van Gaalen SM, Arts MP, et al. BMC Musculoskeletal Disorders 2014, 15:57

Background: Polyetheretherketone (PEEK) cages have been widely used in the treatment of lumbar degenerative disc disorders, and show good clinical results. Read More »

Fundamentals for Achieving the Consistent Skeletal Attachment of Implants

Author(s): Roy D. Bloebaum, Ph.D. University of Utah Department of Orthopaedics

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